Significance of Advanced Platelet Rich Fibrin
Advanced Platelet Rich Fibrin (A-PRF) is a refined version of standard platelet-rich fibrin designed to enhance wound healing. It is produced using lower centrifugation speeds, resulting in a uniform distribution of platelets and a higher concentration of growth factors. This technique allows for a more organized membrane that releases healing factors over an extended period. A-PRF serves as an optimal source of autologous cells, improving cell distribution within the clot and promoting effective tissue regeneration.
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The concept of Advanced Platelet Rich Fibrin in scientific sources
Advanced Platelet Rich Fibrin (A-PRF) is a refined form of PRF, achieved through slower centrifugation, leading to improved platelet distribution and enhanced growth factor concentration, thus offering a superior source of autologous cells in medical applications.
From: Journal of Indian Society of Periodontology
(1) A bioactive material derived from the patient's blood that contains a concentration of platelets to promote tissue regeneration and healing.[1] (2) A-PRF is a modified form of platelet-rich fibrin developed to provide a structurally organized membrane that releases growth factors for a longer duration to aid in wound healing.[2] (3) A type of platelet-rich fibrin (PRF) developed based on low-speed centrifugation that provides an ideal source of autologous cells, with better cell distribution throughout the clot.[3]
From: World Journal of Pharmaceutical Research
(1) A modified version of PRF obtained through slower centrifugation speed, allowing for a more uniform distribution of platelets and a higher concentration of growth factors.[4]