Significance of Active pharmaceutical ingredient
Active pharmaceutical ingredient (API) is the biologically active component of a drug formulation responsible for producing therapeutic effects in medications. This vital substance is integral to ensuring that drugs achieve their intended therapeutic outcomes. APIs can include various chemical compounds that directly affect the body’s biological processes, exemplifying their critical role in drug efficacy. Proper formulation and compatibility with other components are essential for the stability and overall effectiveness of APIs within pharmaceutical products.
Synonyms: Api, Drug substance, Medicinal ingredient, Therapeutic agent, Active ingredient, Medicinal agent
The below excerpts are indicatory and do represent direct quotations or translations. It is your responsibility to fact check each reference.
The concept of Active pharmaceutical ingredient in scientific sources
Active pharmaceutical ingredient (API) is crucial in medications as it refers to the biologically active substances responsible for producing the desired therapeutic effects in patients, making it fundamental to the efficacy of pharmaceutical products.
From: World Journal of Pharmaceutical Research
(1) Refers to the active components in medicines responsible for their therapeutic effects, which can be incorporated into bi-layer tablets.[1] (2) Compounds in pharmaceutical formulations that deliver therapeutic effects, often requiring optimized delivery methods for poorly soluble variants.[2] (3) The substance in a pharmaceutical drug that provides therapeutic effects, specifically regarding the dosage form of Enalapril and Felodipine.[3] (4) The substance in a pharmaceutical product that has therapeutic effects, which needs to be protected through proper formulation.[4] (5) The biologically active components in a pharmaceutical formulation, which in this case are azilsartan and chlorthalidone.[5]
From: Journal of Ayurveda and Holistic Medicine
(1) The biologically active components in a pharmaceutical product that are responsible for the therapeutic effects.[6]
From: AYU (Journal of Research in Ayurveda)
(1) Compounds derived from natural sources that exhibit therapeutic effects and are integral to the efficacy of Ayurvedic medicines.[7]
From: Journal of Ayurveda and Integrative Medicine
(1) The biologically active components in herbal products, which are crucial in determining product efficacy and therapeutic effects.[8]